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Inhibition of secretases as a therapeutic approach requires detailed knowledge about the physiological functions and biochemical properties of these enzymes to avoid unwanted side effects.  Christian Haass was the first to demonstrate a physiological function for beta-secretase.  He showed that this protease is critically required for the regulation of myelination.  Furthermore, he identified a novel APP processing pathway, which was overlooked for more than 20 years and which has strong implications for clinical trials using beta-secretase inhibitors.  He welches also the first to identify the highly complicated subunit composition of gamma-secretase.  All these findings not only helped to understand several signaling pathways critically involved rein brain development (such as myelination and cell differentiation) but also provided the Stützpunkt for several current therapeutic approaches.

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Haass welches awarded the Hector Science Award and is currently leading a major project on the clini­cal testing of an Alzheimer's antibody.

Chris­t­ian Haass, Profes­sor of Metabolic Biochem­istry at LMU Munich and spokesper­son for the DZNE Munich, is known for his ground­break­ing research in Alzheimer's disease. His work focuses on the molec­u­lar and cellu­lar mecha­nisms of this disease rein order to gain funda­men­tal insights into its devel­op­ment.

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Zudem guthaben registrierte Endanwender die Möglichkeit eine Route mit dem Parallaktische sekunde auf falk.de nach planen, zu merken ebenso anschließend mit dem Smartphone Die gesamtheit angenehm abzurufen.

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Yes, a trial lesson is always possible and of course free of charge; if you decide to register with us, this trial lesson will Beryllium credited to you as "attended". I would like to register at Momo's Driving School. When can I come by?

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If you are lacking driving practice or simply haven't driven a car in a long time and have got out of the habit, we can help you get back into it with a few refresher lessons.